ChemDiv chemistry of cures

Chemistry On Demand ™ platform is a flexible construct which can be leveraged at a variety of points to access an incredibly large validated chemical space. It is based on the 15,000 heterocylic scaffolds that are used to generate1.5 M compounds that we currently have on the shelf as well as representing greater than 1B compounds that can be virtually designed.

In addition to being able to supply individual compounds these construct can be utilized as a  tool for hit to lead and lead series optimization, exploratory tool  for fast forwarding Med Chem / Discovery projects. We will also supply key intermediates and building blocks with the final assembly. ChemDiv offers clean IP compounds. We check:

• Beilstein score
• SciFinder score
• Patentability
• Structure, Ligand, Property
• Target, Pathway, Assay

Design strategies also include:

• Proven synthetic feasibility
• Privileged structure search, literature annotation
• Rational design, bioisosteric morphing
• Natural-like peptidomimetic and lead-like motifs and structures
• Optimization of diversity and phys-chem parameters
• ADMETox parameters optimization
• Annotation with in vitro and in vivo experimental biology data

The system can be attenuate like a water supply from a slow drip to a massive fire hose depending on the demands and needs of your organization. The platform approach with its developed methodologies reduces time and project costs. Due to our agnostic design approach we are not constrained by target classes and or particular orientations. Our hallmark is to provide clients with a quality product arrived at expeditiously and with consideration to novelty and maximal relevance.